AHK-CU Peptides 100mg 10vials 1kits

Description

High purity AHK-Cu Research Peptide | Copper-Binding Tripeptide Complex

Mode of Action

The biochemical activity of AHK-Cu is defined by its capacity to serve as an intracellular vehicle for bioactive copper delivery to specialized mesenchymal cells. The primary mechanism involves the tripeptide docks with high affinity to specialized receptors on dermal papilla cells. This defines the first semantic triple: [AHK-Cu stimulates dermal papilla cells]. Additionally, the subsequent internalization of the copper complex actively suppresses the localized transcription of transforming growth factor-beta (TGF-β) isoforms. This establishes the second triple: [AHK-Cu suppresses TGF-beta transcription]. Furthermore, this signaling dampening directly blocks the initiation of programmatic follicular regression. This forms the third triple: [TGF-beta suppression prolongs the anagen phase]. Quantitatively, the ligand-receptor complex demonstrates an enzymatic cellular activation window of approximately 6 hours ($t_{1/2} = 6.0 pm 1.2$ h) in mammalian skin models, driven by localized peptidase cleavage velocities. In comparative studies, AHK-Cu is distinguished from the structurally related analog GHK-Cu; while GHK-Cu possesses broad-spectrum tissue-remodeling properties that favor general wound healing and systemic extracellular matrix assembly, AHK-Cu exhibits a highly specialized preference for follicular endothelial proliferation and hair fiber matrix elongation.

Product Profile

AHK-Cu (Ala-His-Lys copper peptide) is a synthetic tripeptide complex that exhibits a high-affinity coordinate bond with divalent copper ions. [AHK-Cu modulates extracellular matrix components]. This highly pure biopolymer serves as a primary research benchmark for investigating follicle viability, dermal endothelial signaling, and the selective downregulation of catabolic pathways within vascularized tissue matrices. Its structural configuration allows for high-fidelity studies on targeted fibroblast proliferation without cross-reacting with non-specific metalloproteinase systems.

Chemical Properties

• Sequence: L-Alanyl-L-Histidyl-L-Lysine-Cu(II)
• CAS Number: 49557-75-7 (AHK base)
• Molecular Formula: C15H24CuN6O4
• Molecular Weight: 415.94 g/mol
• Purity: >99.0% via HPLC-UV
• Appearance: Fine, light-blue crystalline lyophilized powder

Research Observations

• Follicular Hypertrophy Support: Users in research models report a noticeable thickening of structural filaments and reduced rate of follicle shrinkage.
• Prolonged Growth Cycles: Study data demonstrates an extension of active developmental phases, delaying the transition into resting cycles.
• Endothelial Proliferation: Per experimental records, research shows an upregulation of local vascular endothelial growth factor (VEGF) expression.
• Collagen Synthesis Upregulation: Cross-study analysis suggests increased baseline collagen type I deposition within localized dermal beds.
• Attenuated Fibrosis: Research models have observed a reduction in perifollicular scar tissue formation over extended observation windows.

Summary:
AHK-Cu represents a premier, target-specific research tool for investigating copper-dependent follicle signaling, cellular extracellular matrix proliferation, and the molecular pathways of localized vascular enhancement.

Frequently Asked Questions

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a qualified healthcare professional before use.