Acetic Acid Water 10ml 10vials 1kit-Reconstitution Solution
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Sterile 0.01M Acetic Acid solution for pH-sensitive peptide reconstitution. Maintains peptide stability during dissolution.
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Description
Acetic Acid Water 0.01M ?? Sterile Peptide Reconstitution Solution
Introduction
Acetic Acid Water (0.01M) is a sterile, pH-adjusted aqueous solution specifically formulated for the reconstitution and stabilization of pH-sensitive research peptides. Many peptide sequences, particularly those containing basic amino acid residues or those prone to aggregation in neutral pH environments, require a mildly acidic solvent to achieve complete dissolution and maintain structural integrity. This dilute acetic acid solution serves as the preferred reconstitution medium for specialized peptides including MGF, PEG-MGF, and various growth factor analogs that exhibit poor solubility in sterile water alone.
Technical Specifications
- Concentration: 0.01M (0.06% v/v) Glacial Acetic Acid
- pH Range: 3.5 ?C 4.5 at 25??C
- Sterility: Sterile Filtered, 0.22??m
- Packaging: 10ml sterile glass vial with rubber septum
- Storage: Room temperature (15?C25??C), away from direct light
Applications in Peptide Research
Acetic Acid Water is routinely utilized in the following research applications:
- Reconstitution of pH-Sensitive Peptides: Certain peptides, such as MGF and PEG-MGF, require an acidic environment (pH 4.0?C5.0) for optimal solubility and to prevent aggregation during reconstitution.
- Stabilization of Peptide Secondary Structure: The mild acidic conditions help maintain the native conformation of acid-stable peptides, preserving biological activity during storage and handling.
- Preparation of Stock Solutions: Researchers use this solution to create concentrated peptide stock solutions for subsequent dilution into experimental buffers or carrier solutions.
Usage Guidelines
For optimal results, reconstitute lyophilized peptide powder by injecting 1mL to 2mL of Acetic Acid Water directly into the vial. Gently swirl until the peptide is fully dissolved. For most applications, the reconstituted solution can be further diluted with Bacteriostatic Water or phosphate-buffered saline to achieve the desired working concentration. Once reconstituted, the peptide solution should be stored at 2?C8??C and used within 7?C14 days for maximum stability.
Safety & Storage
This solution is intended for laboratory research purposes only. Store at room temperature in a cool, dry environment. Do not freeze. Keep vial sealed when not in use to maintain sterility. Discard any solution that appears cloudy or contains visible particulate matter.
Summary: Acetic Acid Water (0.01M) provides researchers with a sterile, pH-optimized reconstitution medium for acid-soluble peptides requiring precise pH conditions for dissolution and structural preservation.
FAQ
Why use Acetic Acid Water instead of Bacteriostatic Water?
Certain peptides, particularly growth factor analogs with isoelectric points above 7.0, require an acidic pH to fully dissolve. Acetic Acid Water provides the necessary acidic environment that Bacteriostatic Water (pH 5.5?C6.5) cannot achieve.
What peptides require Acetic Acid Water for reconstitution?
MGF, PEG-MGF, and various IGF-1 analogs are commonly cited in research literature as requiring dilute acetic acid for complete dissolution. Always consult the specific peptide’s technical data sheet.
How should I store reconstituted peptide solutions?
Once reconstituted in Acetic Acid Water, peptide solutions should be refrigerated at 2?C8??C and used within 7?C14 days to maintain stability.
Can I use this solution for all peptides?
No, some peptides are acid-labile and may degrade in low pH environments. Always verify peptide stability in acidic conditions before using this solution.
Is this solution sterile?
Yes, the solution is sterile filtered through a 0.22??m membrane and packaged in a sterile vial for direct research use.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a qualified healthcare professional before use.
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