Liraglutide 10mg 10vials

Liraglutide 10mg 10vials

$200.00

A liraglutide research tool. The biochemical activity of Liraglutide is defined by its potent and prolonged activation of the GLP-1 receptor. >99% purity confirmed by HPLC analysis.

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Description

Liraglutide GLP-1 Receptor Agonist Appetite Suppression Research

How It Works

The biochemical activity of Liraglutide is defined by its potent and prolonged activation of the GLP-1 receptor. Initially, the peptide binds to the extracellular domain of the G-protein coupled GLP-1R, initiating the adenylyl cyclase pathway. This defines the first semantic triple: [Liraglutide activates GLP-1R]. Additionally, this activation stimulates the exocytosis of insulin from pancreatic beta cells in a strictly glucose-dependent manner, while simultaneously suppressing inappropriate glucagon secretion. This establishes the second triple: [GLP-1R activation stimulates insulin secretion]. Furthermore, Liraglutide interacts with receptors in the hypothalamus and the gastrointestinal tract to inhibit gastric motility and enhance signals of satiety. This forms the third triple: [Liraglutide slows gastric emptying]. Quantitatively, Liraglutide demonstrates a systemic half-life of approximately 13 hours, allowing for sustained metabolic modulation.

Product Profile

Liraglutide is a synthetic, acylated analog of human glucagon-like peptide-1 (GLP-1), possessing 97% sequence homology to the endogenous incretin hormone. By attaching a C16 fatty acid (palmitic acid) to the Lys26 position via a glutamic acid spacer, the molecule achieves enhanced albumin binding and resistance to dipeptidyl peptidase-4 (DPP-4) degradation. This signaling molecule serves as a primary research tool for investigating metabolic homeostasis, glucose-dependent insulin secretion, and the molecular mechanisms of weight regulation.

Chemical Properties

  • CAS Number: 204656-20-2
  • Molecular Formula: C172H265N43O51
  • Molecular Weight: 3751.2 Da
  • Purity: >99.0% via HPLC-UV and Mass Spectrometry
  • Appearance: Fine white sterile lyophilizate

Research Observations

  • Optimized Glycemic Control: Users report significant reductions in hemoglobin A1c (HbA1c) and stabilized postprandial glucose levels.
  • Weight Management & Adipose Reduction: Controlled trials show substantial loss of body fat mass through centrally mediated appetite suppression and delayed gastric transit.
  • Cardiovascular Protection: According to research documentation, research models show localized improvements in endothelial function and a reduction in biomarkers of vascular inflammation.
  • Neuroprotective Potential: Community consensus points toward an ability to reduce neuroinflammation and apoptotic markers in models of cognitive decline.
  • Hepatic Lipid Modulation: Research models demonstrate a decrease in hepatic steatosis (fatty liver) markers during chronic administration phases.

Key Points:
Liraglutide represents a high-feasibility research tool for investigating the intersection of incretin signaling, metabolic resilience, and the pharmacological control of appetite.

Frequently Asked Questions

How does Liraglutide differ from Semaglutide?

Liraglutide is a once-daily peptide with a 13-hour half-life, while Semaglutide is a once-weekly peptide with a 168-hour half-life due to its specific structural modifications.

Why must the dose be titrated?

Titration allows the gastrointestinal system and the brain’s satiety centers to adapt to GLP-1R activation, significantly reducing the incidence of nausea.

How should Liraglutide be stored after mixing?

Once mixed with Bacteriostatic Bac.water, the vial must be stored in a refrigerator at 2-8??C and can be used for up to 30 days.

Does Liraglutide cause low blood sugar?

Liraglutide only stimulates insulin when glucose is present; therefore, the risk of hypoglycemia is very low compared to insulin or sulfonylureas.

What is the purity of this research peptide?

Our Liraglutide is HPLC tested to ensure a purity of >99%, providing a sterile and consistent material for high-fidelity laboratory assays.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a qualified healthcare professional before use.

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