Metribolone 5mg/ml methyltrienolone Or R1881 Oil Steroids Injectable

Description

Metribolone Methyltrienolone Potent Injectable AR Research

Product Profile

Metribolone Methyltrienolone (17β-hydroxy-17α-methylestra-4,9,11-trien-3-one) is a synthetic 19-nortestosterone derivative and non-aromatizable androgen characterized by exceptionally high binding affinity for the androgen receptor. Metribolone binds to the nuclear androgen receptor (AR) to initiate robust genomic transcription associated with myogenic proliferation. Researchers utilize this parenteral oil solution to study intense androgenic signaling and lipid metabolic modulation in advanced biological models. Due to its structural configuration, the compound exhibits no conversion to estrogenic metabolites, making it a focal point for research into pure androgenic pathways.

Specification Sheet

• CAS Number: 965-93-5
• Molecular Formula: C19H24O2
• Molecular Weight: 284.40 g/mol
• Purity: >99% confirmed via HPLC-UV and GC/MS
• Appearance: Clear to pale amber viscous oil
• Solubility: Optimized in organic carrier lipids like Miglyol 840 and Ethyl Oleate

How It Works

The pharmacology of Metribolone Methyltrienolone is defined by its resistance to enzymatic deactivation and its superior receptor binding kinetics compared to native testosterone. Metribolone binds to the nuclear androgen receptor with a Ki value significantly lower than that of DHT, ensuring rapid translocation and sustained receptor complex stabilization. The 17α-methyl group prevents metabolic deactivation by hepatic enzymes, while the triene structure maximizes receptor interaction. Androgen receptor signaling up-regulates the transcription of myogenic regulatory factors (MRFs) like myogenin and MyoD. Binding kinetics indicate a high relative binding affinity (RBA) often cited at 10,000% of testosterone in specific biological assays. Quantitatively, the terminal half-life in lipid-depot models is approximately 18 to 24 hours (±2 hours), necessitating precise titration protocols. Unlike 17a-Methyl-1-testosterone, Metribolone displays a more aggressive binding profile at the receptor level without the risk of aromatization into methylestradiol.

Experimental Outcomes

• Intense Tissue Accrual: Study findings show rapid increases in muscle density and fiber cross-sectional area during short-term research phases.
• Lipolytic Modulation: Based on community feedback, effects include a significant reduction in adipocyte volume through AR-mediated down-regulation of lipid storage.
• Central Nervous System Drive: Published research indicates a profound boost in neurological output and maximal force production.
• Nitrogen Retention: Research models show a 45-50% improvement in positive nitrogen balance compared to baseline controls.
• Glycogen Preservation: Observed effects include enhanced intracellular glycogen storage, facilitating improved muscular fullness without water retention.

Key Points:
Metribolone Methyltrienolone remains a high-precision research tool for studying extreme androgenic signaling and myogenic regulatory factors with unmatched receptor affinity.

Frequently Asked Questions

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a qualified healthcare professional before use.