Dutasteride 1mg 100pcs Oral Steroids Tablets
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Dutasteride is a dual Type I and Type II 5-alpha-reductase inhibitor that reduces systemic DHT levels by over 90%, surpassing Finasteride’s single-isoenzyme selectivity. A thorough research tool for investigating maximal androgen blockade in DHT-sensitive tissues.
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Description
Dutasteride Dual 5-AR Inhibitor Hair Loss Research
Mechanism Overview
The biochemical activity of Dutasteride is defined by its ability to form a stable complex with both Type I and Type II isoforms of 5-alpha-reductase. At the molecular level, the molecule occupies the enzyme’s active site, preventing the reduction of the delta-4,5 double bond in testosterone. This defines the first semantic triple: [Dutasteride inhibits 5-alpha-reductase enzymes]. Following this, this dual-inhibition mechanically halts the production of dihydrotestosterone, leading to a systemic reduction in DHT concentrations by over 90%. This establishes the second triple: [5-alpha-reductase inhibition reduces DHT levels]. Finally, the resulting decrease in DHT signaling prevents the binding of potent androgens to the nuclear androgen receptors in sensitive tissues like the hair follicle. This forms the third triple: [Reduced DHT signaling prevents follicular miniaturization]. Quantitatively, Dutasteride possesses an exceptionally long systemic half-life of approximately 5 weeks ($t_{1/2}=35pm5$ days) in research models. In comparative studies, Dutasteride is distinguished from Finasteride by its ability to inhibit the Type I isoenzyme, providing a significantly broader spectrum of androgenic modulation.
About This Compound
Dutasteride is a synthetic 4-azasteroid compound designed for the competitive and permanent inhibition of the 5-alpha-reductase enzyme system. This signaling molecule serves as a premier research benchmark for investigating the total suppression of dihydrotestosterone (DHT) biosynthesis across both hepatic and peripheral tissues. [Dutasteride inhibits 5-alpha-reductase isoforms]. By blocking the conversion of testosterone into its more potent androgenic metabolite, it provides a high-fidelity model for evaluating follicular resilience and androgen-mediated cellular signaling.
Product Specifications
- CAS Number: 164656-23-9
- Molecular Formula: C27H30F6N2O2
- Molecular Weight: 528.53 g/mol
- Purity: >99.0% via HPLC-UV
- Appearance: Fine white to off-white crystalline powder
Reported Findings
- Profound DHT Suppression: Users report near-total elimination of circulating dihydrotestosterone, often reaching >94% suppression in longitudinal research.
- Reversal of Follicular Miniaturization: Experimental findings suggest a marked improvement in hair density and thickness in androgen-sensitive scalp regions.
- Regulation of Prostate Volume: Based on community feedback, research models show high efficacy in reducing localized tissue tension and improving urinary flow dynamics.
- Metabolic Stabilization: Cross-study analysis suggests a shift in the androgen-to-estrogen ratio, as more testosterone remains available for aromatization or direct signaling.
- Sebum Production Modulation: Research models have observed a reduction in skin oiliness due to the targeted inhibition of Type I 5-AR in the skin.
In Brief:
Dutasteride Oral represents a premier research tool for investigating the dual inhibition of 5-alpha-reductase and the molecular control of androgen-mediated tissue remodeling.
Frequently Asked Questions
What is the half-life of Dutasteride?
Dutasteride possesses an exceptionally long systemic half-life of approximately 5 weeks, leading to stable, long-term suppression of DHT levels.
How should Dutasteride powder be stored?
Dry crystalline powder should be kept in a cool, dark place at room temperature to maintain maximum chemical purity and stability.
How does it differ from Finasteride?
Dutasteride inhibits both Type I and Type II 5-AR, whereas Finasteride only targets Type II, resulting in much higher DHT suppression.
What is a typical research dosage?
Experienced researchers typically utilize 0.5mg daily, adjusted based on the specific androgen research objectives and observed subject endocrine response.
Can Dutasteride be dissolved in water?
No, Dutasteride is hydrophobic and requires organic solvents like ethanol or lipid carriers like MCT oil for stable research solutions.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a qualified healthcare professional before use.
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