GHRP-2 Acetate 10mg 10vials
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GHRP-2 Acetate (Pralmorelin) is a second-generation synthetic hexapeptide that acts as a potent ghrelin receptor agonist, triggering reliable growth hormone release from pituitary somatotrophs. With higher GHSR-1a affinity than GHRP-6 and minimal appetite stimulation, it is ideal for evaluating GH pulsatility.
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Description
GHRP-2 Acetate Potent GH Secretagogue Research Peptide
About This Compound
GHRP-2 Acetate, technically recognized in scientific literature as Pralmorelin, is a second-generation synthetic hexapeptide functioning as a highly selective growth hormone secretagogue. This compound actively stimulates endogenous somatotroph function via the ghrelin pathway, serving as a primary research tool for evaluating pituitary endocrine release dynamics.
Specification Sheet
- CAS Number: 158861-67-7
- Molecular Formula: C45H55N9O6
- Molecular Weight: 818.0 g/mol
- Purity: >99% (HPLC validated)
- Appearance: Sterile filtered white lyophilized powder
How It Works
GHRP-2 Acetate functions as a potent agonist at the ghrelin receptor (GHSR-1a). The peptide binds directly to the pituitary somatotrophs to initiate a cyclic AMP-dependent intracellular signaling cascade. This receptor activation triggers a substantial influx of calcium ions, fundamentally forcing immediate growth hormone vesicle exocytosis. Compared to its predecessor GHRP-6, GHRP-2 possesses a noticeably higher binding affinity (Ki ?? 2.1 nM) for the GHSR-1a receptor, which yields a quantitatively larger acute GH pulse. Furthermore, the specific molecular structure of GHRP-2 minimizes the secondary pathway activation that typically triggers extreme gastric motility. The compound exhibits a brief in vivo biological half-life of approximately 30 to 60 minutes.
Research Observations
- Investigators observe accelerated muscular recovery and enhanced joint tissue repair following heavy resistance training.
- Published research indicates a slight but manageable increase in systemic appetite, substantially less intense than GHRP-6.
- Cross-study analysis suggests improved sleep latency and deeper slow-wave sleep cycles.
- Researchers note observable dose-dependent increases in systemic nitrogen retention over sustained multi-week protocols.
Key Points:
GHRP-2 Acetate offers researchers a highly potent, targeted secretagogue for maximizing physiological growth hormone pulses with mitigated extreme hunger side effects.
Frequently Asked Questions
[Q] How is GHRP-2 different from GHRP-6?
GHRP-2 typically induces a significantly larger growth hormone pulse while causing drastically less appetite stimulation compared to GHRP-6.
[Q] When is the optimal time for administration?
Users report the best physiological response when injected on a strictly empty stomach, typically upon waking and immediately before sleep.
[Q] Does GHRP-2 raise cortisol levels?
Yes, clinical research and user data indicate that high dosages can trigger transient, dose-dependent increases in both cortisol and prolactin.
[Q] How long is the reconstituted peptide viable?
When mixed with Bacteriostatic Bac.water and stored consistently between 2??C and 8??C, the solution remains potent for approximately 21 days.
[Q] Can I mix this with CJC-1295?
Yes, researchers frequently observe profound synergistic effects when a ghrelin agonist is administered concurrently with a GHRH analog.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a qualified healthcare professional before use.
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